{"id":37,"date":"2026-11-06T09:06:23","date_gmt":"2026-11-06T09:06:23","guid":{"rendered":"https:\/\/healthcare.hibisports.com\/?p=37"},"modified":"2026-11-06T09:06:23","modified_gmt":"2026-11-06T09:06:23","slug":"why-estrogen-patches-are-so-hard-to-find-right-now","status":"publish","type":"post","link":"https:\/\/healthcare.hibisports.com\/?p=37","title":{"rendered":"Why Estrogen Patches Are So Hard to Find Right Now"},"content":{"rendered":"<div id=\"health-sc-page_1-0\" class=\"comp health-sc-page mntl-sc-page mntl-block structured-content article-content expert-content right-rail__offset lock-journey\" data-sc-sticky-offset=\"60\" data-sc-ad-label-height=\"24\" data-sc-ad-track-spacing=\"100\" data-sc-min-track-height=\"250\" data-sc-max-track-height=\"600\" data-sc-breakpoint=\"50em\" data-sc-load-immediate=\"4\" data-sc-content-positions=\"[400, 1400, 1400, 1700, 2000, 2200, 2400, 2600, 2800]\" data-bind-scroll-on-start=\"true\">\n<div id=\"health-sc-block-callout--key-takeaway_1-0\" class=\"comp health-sc-block-callout--key-takeaway health-sc-block-callout-base mntl-sc-block-callout mntl-block theme-key-takeaway theme-key-takeaway\" data-tracking-id=\"mntl-sc-block-callout\" data-tracking-container=\"true\">\n<h3 id=\"mntl-sc-block-callout-heading_1-0\" class=\"comp mntl-sc-block-callout-heading mntl-text-block\">Key Takeaways<\/h3>\n<div id=\"mntl-sc-block-callout-body_1-0\" class=\"comp mntl-sc-block-callout-body mntl-text-block expert-content\">\n<ul>\n<li>The FDA has removed the black box warning on hormone therapy, which had previously discouraged its use due to overstated risks.<\/li>\n<li>Estrogen patches are a safer alternative to oral pills for menopause symptoms because they bypass the liver, reducing the risk of blood clots, heart attack, and stroke.<\/li>\n<li>The increased demand for estrogen patches after the FDA&#8217;s decision has led to temporary shortages, but alternatives are available.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p id=\"mntl-sc-block_2-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Estrogen patches are in such high demand that they&#8217;re becoming harder to find.\n<\/p>\n<div id=\"mntl-sc-block_3-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_4-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> The shortage comes amid a broader shift in the perception of how safe hormone therapy is. In November 2025, the Food and Drug Administration (FDA) removed a longstanding black box warning on hormone therapy.\n<\/p>\n<div id=\"mntl-sc-block_5-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_6-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Originally issued in 2003 based on research from the Women\u2019s Health Initiative, the warning stated that hormone therapy, including estrogen pills, patches, and gels, could increase the risk of heart disease, breast cancer, and dementia.<span class=\"mntl-inline-citation mntl-dynamic-tooltip--trigger\" data-id=\"#citation-1\" tabindex=\"0\">1<\/span> After reassessing the now-outdated study, the FDA determined the risks were overgeneralized and may have discouraged appropriate use of treatments that can significantly improve menopause symptoms.\n<\/p>\n<div id=\"mntl-sc-block_7-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\">\n<div id=\"mm-ads-native_1-0\" class=\"comp mm-ads-native \" style=\"--native-ad-height: auto\" data-right-rail-index=\"1\">\n<div id=\"mm-ads-native__adunit_1-0\" class=\"comp mm-ads-native__adunit mm-ads-gpt-dynamic-adunit mm-ads-gpt-adunit scads-to-load gpt native js-immediate-ad js-immediate-ad-loaded\">\n<div id=\"native\" class=\"wrapper\" data-type=\"native\" data-pos=\"native\" data-priority=\"4\" data-sizes=\"[[1, 3],&quot;fluid&quot;]\" data-rtb=\"false\" data-wait-for-third-party=\"false\" data-targeting=\"{}\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><span class=\"heading-toc\" id=\"toc-why-are-estrogen-patches-so-popular-now\"><\/span><\/p>\n<h2 id=\"mntl-sc-block_8-0\" class=\"comp mntl-sc-block health-sc-block-heading mntl-sc-block-heading\"> <span class=\"mntl-sc-block-heading__text text-title-300\"> Why Are Estrogen Patches So Popular Now? <\/span> <\/h2>\n<p id=\"mntl-sc-block_9-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Estrogen patches (also known as transdermal estradiol) are one form of <a class=\"recommendation-inline-link\" href=\"https:\/\/www.verywellhealth.com\/hormone-therapy-for-menopause-4154740\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"internalLink\" data-ordinal=\"1\" rel=\"noopener noreferrer\">hormone treatment for menopause<\/a> that helps deliver estrogen through your skin, as opposed to oral options such as pills.\n<\/p>\n<div id=\"mntl-sc-block_10-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_11-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Oral pills are processed by the liver, which may raise the risk of blood clots. Estrogen patches can bypass the liver metabolism process and reduce the risk of clots, heart attacks, and strokes, according to <a href=\"https:\/\/www.mayo.edu\/research\/faculty\/faubion-stephanie-s-m-d-m-b-a\/bio-20199366\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\">Stephanie S. Faubion, MD, MBA<\/a>, the director of the Mayo Clinic Center for Women\u2019s Health and medical director of The Menopause Society.\n<\/p>\n<div id=\"mntl-sc-block_12-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_13-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Healthcare providers commonly prescribe transdermal patches for people going through menopause and <a class=\"recommendation-inline-link\" href=\"https:\/\/www.verywellhealth.com\/is-this-perimenopause-3522477\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"internalLink\" data-ordinal=\"1\" rel=\"noopener noreferrer\">perimenopause<\/a> as a safer, lower-risk alternative to oral pills.<span class=\"mntl-inline-citation mntl-dynamic-tooltip--trigger\" data-id=\"#citation-6\" tabindex=\"0\">2<\/span> Estrogen patches, like other forms of hormone therapy, can reduce common menopause symptoms such as <a class=\"recommendation-inline-link\" href=\"https:\/\/www.verywellhealth.com\/vasomotor-symptoms-2322781\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"internalLink\" data-ordinal=\"2\" rel=\"noopener noreferrer\">hot flashes and night sweats<\/a>. They may also relieve <a class=\"recommendation-inline-link\" href=\"https:\/\/www.verywellhealth.com\/vaginal-dryness-causes-and-treatments-3522435\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"internalLink\" data-ordinal=\"3\" rel=\"noopener noreferrer\">vaginal dryness or itching<\/a>.<span class=\"mntl-inline-citation mntl-dynamic-tooltip--trigger\" data-id=\"#citation-2\" tabindex=\"0\">3<\/span>\n<\/p>\n<div id=\"mntl-sc-block_14-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_15-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> The FDA\u2019s updated stance on hormone therapy safety is driving broader acceptance of estrogen patches, prompting more people in menopause to seek out this form of treatment.\n<\/p>\n<div id=\"mntl-sc-block_16-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_17-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> \u201cThe FDA black box warning ended up gatekeeping one of the most powerful tools we have to improve women\u2019s quality of life and support long-term health,\u201d <a href=\"https:\/\/www.drsomi.com\/\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" rel=\"nofollow noopener\" target=\"_blank\">Somi Javaid, MD<\/a>, a board-certified OB\/GYN, surgeon, and founder of HerMD, told Verywell.\n<\/p>\n<div id=\"mntl-sc-block_18-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_19-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Use of hormone therapy is expected to rise further, putting additional strain on supply. &#8220;I think the current estrogen patch shortage is temporary, but we should&#8217;ve been better prepared for this moment,&#8221; Javaid said.\n<\/p>\n<div id=\"mntl-sc-block_20-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<div id=\"mntl-sc-block_21-0\" class=\"comp mntl-sc-block health-sc-block-digiohembed mntl-block\">\n<div id=\"mntl-sc-block-digiohembed_1-0\" class=\"comp mntl-sc-block-digiohembed mntl-block\">\n<div id=\"lightbox-inline-form-d6b1ce8f-ffcf-49f7-9130-c9a0962426b2\" class=\"mntl-sc-block-digiohembed__container digioh-inline-unit digioh-inline-unit--sc\" data-guid=\"lightbox-inline-form-d6b1ce8f-ffcf-49f7-9130-c9a0962426b2\" data-title=\"\">\n<\/div>\n<\/div>\n<\/div>\n<div id=\"mntl-sc-block_22-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<div id=\"health-sc-block-spotlight--mid-circ_1-0\" class=\"comp health-sc-block-spotlight--mid-circ mntl-sc-block-spotlight--mid-circ mntl-block theme-mid-circ theme-mid-circ\" data-use-proximity=\"true\">\n<h2 id=\"midcirc__heading_1-0\" class=\"comp midcirc__heading mntl-text-block\">Related Stories<\/h2>\n<div id=\"midcirc__card-list_1-0\" class=\"comp midcirc__card-list mntl-block\"><a href=\"https:\/\/www.verywellhealth.com\/facial-flushing-caused-by-menopause-1069268\" rel=\"nocaes\" data-card-index=\"0\" data-click-tracked=\"false\" id=\"midcirc-card_1-0\" class=\"midcirc-card mntl-midcirc-card mntl-text-link \" data-tracking-container=\"true\"><\/p>\n<div id=\"midcirc-card__title_1-0\" class=\"comp midcirc-card__title mntl-text-block\">Facial Flushing and Hot Flashes<\/div>\n<div id=\"midcirc-card__image-wrapper_1-0\" class=\"comp midcirc-card__image-wrapper mntl-block\">\n<div class=\"midcirc-card__image mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\" style=\"padding-bottom:66.6%;\">\n<img data-src=\"https:\/\/www.verywellhealth.com\/thmb\/1ofz6ZguL657FuI6gOBxSme0H88=\/300x200\/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)\/exhausted-mature-woman-entering-menopause-973154158-d8967a0cf91b403282b7401ca9dc627a.jpg\" width=\"300\" height=\"200\" alt=\"Exhausted mature woman entering menopause\" class=\" universal-image__image lazyloadwait\"><br \/>\n<noscript><br \/>\n<img\nsrc=\"https:\/\/www.verywellhealth.com\/thmb\/1ofz6ZguL657FuI6gOBxSme0H88=\/300x200\/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)\/exhausted-mature-woman-entering-menopause-973154158-d8967a0cf91b403282b7401ca9dc627a.jpg\"\nwidth=\"300\"\nheight=\"200\"\nclass=\"img--noscript universal-image__image\"\nalt=\"Exhausted mature woman entering menopause\"\n\/><br \/>\n<\/noscript>\n<\/div>\n<\/div>\n<\/div>\n<p><\/a><br \/>\n<a href=\"https:\/\/www.verywellhealth.com\/cool-ways-to-stop-hot-flashes-2322681\" rel=\"nocaes\" data-card-index=\"1\" data-click-tracked=\"false\" id=\"midcirc-card_2-0\" class=\"midcirc-card mntl-midcirc-card mntl-text-link \" data-tracking-container=\"true\"><\/p>\n<div id=\"midcirc-card__title_2-0\" class=\"comp midcirc-card__title mntl-text-block\">What Can I Do About Hot Flashes?<\/div>\n<div id=\"midcirc-card__image-wrapper_2-0\" class=\"comp midcirc-card__image-wrapper mntl-block\">\n<div class=\"midcirc-card__image mntl-image card__media universal-image__container\">\n<div class=\"img-placeholder\" style=\"padding-bottom:66.6%;\">\n<img data-src=\"https:\/\/www.verywellhealth.com\/thmb\/TjGMyyEGPcuCYWnQ881CdxWfDvg=\/300x200\/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)\/woman-suffers-from-heat-in-the-office-or-at-home-1198411657-665d2cfae03a43daa1587916dfb97d93.jpg\" width=\"300\" height=\"200\" alt=\"Woman suffers from heat in the office or at home\" class=\" universal-image__image lazyloadwait\"><br \/>\n<noscript><br \/>\n<img\nsrc=\"https:\/\/www.verywellhealth.com\/thmb\/TjGMyyEGPcuCYWnQ881CdxWfDvg=\/300x200\/filters:no_upscale():max_bytes(150000):strip_icc():format(webp)\/woman-suffers-from-heat-in-the-office-or-at-home-1198411657-665d2cfae03a43daa1587916dfb97d93.jpg\"\nwidth=\"300\"\nheight=\"200\"\nclass=\"img--noscript universal-image__image\"\nalt=\"Woman suffers from heat in the office or at home\"\n\/><br \/>\n<\/noscript>\n<\/div>\n<\/div>\n<\/div>\n<p><\/a><\/div>\n<\/div>\n<div id=\"mntl-sc-block_24-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p><span class=\"heading-toc\" id=\"toc-is-estrogen-linked-to-longevity\"><\/span><\/p>\n<h2 id=\"mntl-sc-block_25-0\" class=\"comp mntl-sc-block health-sc-block-heading mntl-sc-block-heading\"> <span class=\"mntl-sc-block-heading__text text-title-300\"> Is Estrogen Linked to Longevity? <\/span> <\/h2>\n<p id=\"mntl-sc-block_26-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Alongside rising demand for estrogen patches, social media has fueled claims that estrogen can boost longevity and reduce the risk of age-related conditions like dementia. Experts say the science isn&#8217;t as clear-cut as people may believe.\n<\/p>\n<div id=\"mntl-sc-block_27-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_28-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> &#8220;The internet loves a simple story: estrogen equals longevity. But the real answer is more nuanced,&#8221; Javaid said. &#8220;What the research consistently points to is that timing matters. When estrogen therapy is started earlier, closer to the perimenopause\/menopause transition, the risk\u2013benefit profile looks more favorable.&#8221;\n<\/p>\n<div id=\"mntl-sc-block_29-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_30-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Research presented at the 2025 Annual Meeting of The Menopause Society found that starting hormone therapy during perimenopause can help improve long-term health outcomes as you age.<span class=\"mntl-inline-citation mntl-dynamic-tooltip--trigger\" data-id=\"#citation-3\" tabindex=\"0\">4<\/span>\n<\/p>\n<div id=\"mntl-sc-block_31-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_32-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> Outside of being a reproductive hormone, <a class=\"recommendation-inline-link\" href=\"https:\/\/www.verywellhealth.com\/menopause-hormone-therapy-and-dementia-risk-8384302\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"internalLink\" data-ordinal=\"1\" rel=\"noopener noreferrer\">estrogen acts as a protective agent for your brain<\/a> to shield it from degeneration or cell loss.<span class=\"mntl-inline-citation mntl-dynamic-tooltip--trigger\" data-id=\"#citation-4\" tabindex=\"0\">5<\/span>\n<\/p>\n<div id=\"mntl-sc-block_33-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_34-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> &#8220;Loss of estrogen during the menopause transition is associated with brain changes that researchers believe may contribute to dementia risk later in life,&#8221; Javaid said. &#8220;Estrogen isn&#8217;t a guaranteed longevity drug, but for most patients\u2014especially when started at the right time\u2014it may support healthier aging by protecting our bone, brain, and heart, while also improving day-to-day quality of life.&#8221;\n<\/p>\n<div id=\"mntl-sc-block_35-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p><span class=\"heading-toc\" id=\"toc-estrogen-patch-alternatives-are-available\"><\/span><\/p>\n<h2 id=\"mntl-sc-block_36-0\" class=\"comp mntl-sc-block health-sc-block-heading mntl-sc-block-heading\"> <span class=\"mntl-sc-block-heading__text text-title-300\"> Estrogen Patch Alternatives Are Available <\/span> <\/h2>\n<p id=\"mntl-sc-block_37-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> If you&#8217;re actively using estrogen patches as a part of your menopause treatment, there&#8217;s no need to worry about the shortage right now. While there is a chance for symptoms to rebound, the side effects of abruptly discontinuing estrogen patches aren&#8217;t dangerous.\n<\/p>\n<div id=\"mntl-sc-block_38-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_39-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> &#8220;Once an estrogen patch is removed, hot flashes will usually return within a day or two. Perhaps a little longer, depending on the frequency and severity of the symptoms before estrogen usage,&#8221; said <a href=\"https:\/\/providers.texastechphysicians.com\/provider\/robert-kauffman\/2676324\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" rel=\"nofollow noopener\" target=\"_blank\">Robert Kauffman, MD<\/a>, a professor of Obstetrics and Gynecology at the Texas Tech University Health Sciences Center School of Medicine. &#8220;With hot flashes, there may be disrupted sleep. These are not life-threatening, but are quality-of-life issues.&#8221;\n<\/p>\n<div id=\"mntl-sc-block_40-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_41-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> If you stop using estrogen patches and notice spotting or unexpected bleeding, it&#8217;s important to reach out to your healthcare provider.\n<\/p>\n<div id=\"mntl-sc-block_42-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_43-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> There are alternatives you can use to minimize symptom rebound or unwanted side effects if your regular patches are out of stock.\n<\/p>\n<div id=\"mntl-sc-block_44-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_45-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> The most common alternatives are other transdermal options such as estrogen spray, estrogen gel, and vaginal rings. If you&#8217;d like to continue using patches, you might be able to switch to a lower-dose patch or use a generic patch if you&#8217;re currently using a branded prescription, Kauffman said.\n<\/p>\n<div id=\"mntl-sc-block_46-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_47-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> It may also help to call other pharmacies in your area to see if they have your patch in stock. If all else fails, you can ask your healthcare provider to prescribe you an oral estrogen pill for the time being.\n<\/p>\n<div id=\"mntl-sc-block_48-0\" class=\"comp mntl-sc-block mntl-sc-block-adslot mntl-block\"><\/div>\n<p id=\"mntl-sc-block_49-0\" class=\"comp mntl-sc-block mntl-sc-block-html\"> &#8220;The benefits are much more likely to exceed the very small risk of using oral estrogen for a defined duration,&#8221; Kauffman said.\n<\/p>\n<\/div>\n<div id=\"post-article_1-0\" class=\"comp post-article mntl-block\">\n<div id=\"breadcrumbs--chips_1-0\" class=\"comp breadcrumbs--chips mntl-universal-breadcrumbs--chips mntl-block\">\n<div id=\"mntl-breadcrumbs__read-more_1-0\" class=\"comp mntl-breadcrumbs__read-more mntl-text-block text-title-100\">Read More:<\/div>\n<ul id=\"mntl-universal-breadcrumbs_1-0\" class=\"comp mntl-universal-breadcrumbs mntl-block breadcrumbs\" data-tracking-container=\"true\">\n<li id=\"mntl-breadcrumbs__item_1-0\" class=\"comp mntl-breadcrumbs__item mntl-block text-utility-200\"><a href=\"https:\/\/www.verywellhealth.com\/health-a-z-4014770\" rel=\"nocaes\" class=\"mntl-text-link mntl-breadcrumbs__link\" id=\"mntl-text-link_5-0\" data-tracking-container=\"true\"><span class=\"link__wrapper\">Health A-Z<\/span><\/a><\/li>\n<li id=\"mntl-breadcrumbs__item_2-0\" class=\"comp mntl-breadcrumbs__item mntl-block text-utility-200\"><a href=\"https:\/\/www.verywellhealth.com\/menopause-overview-4581933\" rel=\"nocaes\" class=\"mntl-text-link mntl-breadcrumbs__link\" id=\"mntl-text-link_6-0\" data-tracking-container=\"true\"><span class=\"link__wrapper\">Menopause<\/span><\/a><\/li>\n<li id=\"mntl-breadcrumbs__item_3-0\" class=\"comp mntl-breadcrumbs__item mntl-block text-utility-200\"><a href=\"https:\/\/www.verywellhealth.com\/menopause-treatment-overview-4581932\" rel=\"nocaes\" class=\"mntl-text-link mntl-breadcrumbs__link\" id=\"mntl-text-link_7-0\" data-tracking-container=\"true\"><span class=\"link__wrapper\">Treatment<\/span><\/a><\/li>\n<\/ul>\n<\/div>\n<div id=\"sources_1-0\" class=\"comp sources mntl-block\">\n<div id=\"mntl-article-sources_1-0\" class=\"comp mntl-article-sources mntl-expandable-block\" data-scroll-offset=\"70\">\n<div class=\"loc toggle-content\">\n<div id=\"mntl-article-sources__wrapper_1-0\" class=\"comp mntl-article-sources__wrapper mntl-block\" data-click-tracked=\"true\" tabindex=\"0\"><span id=\"mntl-article-sources__heading_1-0\" class=\"comp mntl-article-sources__heading mntl-text-block\">5 Sources<\/span><br \/>\n<svg class=\"icon show-icon \">\n<use xmlns_xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink_href=\"#show-icon\" href=\"#show-icon\"><\/use>\n<\/svg><br \/>\n<svg class=\"icon hide-icon \">\n<use xmlns_xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink_href=\"#hide-icon\" href=\"#hide-icon\"><\/use>\n<\/svg><\/div>\n<\/div>\n<div class=\"loc expandable-content\">\n<div id=\"source-guidelines_1-0\" class=\"comp source-guidelines mntl-text-block\">Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our <a href=\"\/verywell-editorial-process-4777042\">editorial process<\/a> to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.<\/div>\n<div id=\"mntl-article-sources__citation-sources_1-0\" class=\"comp mntl-article-sources__citation-sources mntl-citation-sources mntl-sources\" data-tracking-container=\"true\">\n<ol class=\"mntl-sources__content\">\n<li class=\"mntl-sources__source\" id=\"citation-1\">\n<p>U.S. Food and Drug Administration. <a href=\"https:\/\/www.fda.gov\/drugs\/drug-alerts-and-statements\/fda-requests-labeling-changes-related-safety-information-clarify-benefitrisk-considerations\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\">FDA Requests Labeling Changes Related to Safety Information to Clarify the Benefit\/Risk Considerations for Menopausal Hormone Therapies<\/a>.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-6\">\n<p>Gold\u0161tajn M\u0160, Miku\u0161 M, Ferrari FA, et al.<a href=\"https:\/\/doi.org\/10.1007\/s00404-022-06647-5\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\"> <\/a><a href=\"https:\/\/doi.org\/10.1007\/s00404-022-06647-5\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"2\" target=\"_blank\" rel=\"noopener\">Effects of transdermal versus oral hormone replacement therapy in postmenopause: a systematic review<\/a>.&nbsp;<em>Arch Gynecol Obstet<\/em>. 2023;307(6):1727-1745. doi:10.1007\/s00404-022-06647-5<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-2\">\n<p>Harvard Health Publishing. <a href=\"https:\/\/www.health.harvard.edu\/womens-health\/understanding-hormone-therapy-for-menopausal-symptoms\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\">Understanding hormone therapy for menopausal symptoms<\/a>.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-3\">\n<p>The Menopause Society. <a href=\"https:\/\/menopause.org\/press-releases\/when-women-initiate-estrogen-therapy-matters\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\">When Women Initiate Estrogen Therapy Matters<\/a>.<\/p>\n<\/li>\n<li class=\"mntl-sources__source\" id=\"citation-4\">\n<p>Lu J, Xian TJ, Li CJ, Wang Y. <a href=\"https:\/\/doi.org\/10.3389\/fnagi.2025.1671552\" data-component=\"link\" data-source=\"inlineLink\" data-type=\"externalLink\" data-ordinal=\"1\" target=\"_blank\" rel=\"noopener\">The estrogen-brain interface in neuroinflammation: a multidimensional mechanistic insight<\/a>.&nbsp;<em>Front Aging Neurosci<\/em>. 2025;17:1671552. doi:10.3389\/fnagi.2025.1671552<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div 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Estrogen patches are a safer alternative to oral pills for menopause symptoms because they bypass the liver,&#8230; <\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-37","post","type-post","status-publish","format-standard","hentry","category-chua-phan-loai"],"_links":{"self":[{"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=\/wp\/v2\/posts\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37"}],"version-history":[{"count":0,"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=\/wp\/v2\/posts\/37\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthcare.hibisports.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}